Proton pump inhibitors (PPIs) block acid production in your stomach. H2 blockers can cause side effects such as: famotidine (Calmicid, Fluxid, Pepcid AC).H2 blockers are available OTC and by prescription. However, they can provide longer symptom relief, lasting 8 to 12 hours. This means they act more slowly than antacids. Typically, they start to work within an 1 to 3 hours of when you take them. H2 blockers reduce the amount of acid produced in your stomach to lower your risk of heartburn. Stronger versions of these drugs are also available with a prescription. Other OTC medications help treat GERD symptoms by reducing the amount of acid your stomach makes. In this article, we detail the different OTC treatments available for GERD, how they help, and when you should see a doctor. Some offer immediate relief, while others help to prevent symptoms from returning. Over-the-counter (OTC) medications are often among the first people use to treat symptoms of gastroesophageal reflux disease (GERD), such as heartburn and regurgitation.ĭifferent types of OTC drugs for GERD help in different ways. Famotidine is in the same class as ranitidine and works the same way but has not been found to contain unacceptable levels of NDMA. Ranitidine, brand name Zantac, is now marketed as Zantac 360, which contains a different active ingredient (famotidine). Instead of taking unused ranitidine products to a drug take-back site, dispose of them according to the product’s instructions or by following the FDA’s guidance. If you’re taking OTC ranitidine, stop taking the drug and talk with your doctor about alternative options. If you’re prescribed ranitidine, talk with your doctor about safe alternative options before stopping the drug. This recommendation was made because unacceptable levels of NDMA, a probable carcinogen (cancer-causing chemical), were found in some ranitidine products. In April 2020, the Food and Drug Administration (FDA) requested that all forms of prescription and over-the-counter (OTC) ranitidine (Zantac) be removed from the U.S.
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